The Stress - Depression Connection, Explained

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The brain is incredibly complex. But we may now be one step closer on to understanding how it works. I'm Kyle Kittleson. This is MedCircle News.

According to Forbes.com, a recent study using mice found that stress and depression could be related. When researchers affected the mice brains with repeated bouts of stress, they observed immune responses that released cytokines. These are proteins that are used to indicate inflammation in mice and humans. This lead affected the prefrontal cortex of the brain and caused behavior in line with depression.

Or, more simply put, “the researchers were able to observe a series of falling dominoes starting with stress, leading to inflammation, leading to depression, all playing out through an immune response in the brain.”

Of course, what affects mice doesn’t necessarily mean it will affect humans in the same way. However, it is an interesting discovery and with lots of potential implications.

One implication would be developing new medication to treat people who suffer from stress-induced depression. These new medications would likely target the stress components rather than neurotransmitters like serotonin and dopamine, which is today’s standard when it comes to antidepressants.

For more information on depression become a subscriber when you visit MedCircle.com. There you can also watch our original series Debunking Depression: Harnessing Your Hardwired Nature to Be Happy. I’m Kyle Kittleson, and remember, whatever you're going through, you got this.

Source: Forbes.com


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