Vitamin D status is associated with treatment failure and duration of illness in Nepalese children with severe pneumonia

To investigate the association of vitamin D status and outcome of severe childhood pneumonia, we estimated the associations between vitamin D status and illness duration and treatment failure using the two most commonly used cutoffs for vitamin D insufficiency and after adjusting for possible confounders. Children with 25(OH)D concentrations <50 nmol/l had significantly higher risk for longer duration of illness and higher risk for treatment failure compared with children with higher 25(OH)D concentrations. This association was stronger in children who tested positive for one of the common respiratory viruses than in those who did not. These results could indicate that...

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