Scientists Discover Schizophrenia & Bipolar Gene Roles in Brain Development

Scientists Discover Schizophrenia & Bipolar Gene Roles in Brain Development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression. It's the first time these molecules, which are associated with the disrupted-in-schizophrenia 1 (DISC1) protein linked to mental disorders, have been identified. The scientists developed new tools involving stem cells to determine chemical reactions the proteins use to influence cell functions and nerve growth in people. "This moves science closer to opportunities for treatment for serious mental illness," said Marcelo P. Coba, the study author and professor of psychiatry at the Zilkha Neurogenetic Institute at the...

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