New Treatment for Ulcerative Colitis Approved

U.S. Food and Drug Administration approval of Xeljanz (tofacitinib) has been expanded to include adults with active moderate-to-severe ulcerative colitis, the agency said Wednesday.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, characterized by recurring flares of abdominal pain and bloody diarrhea. Symptoms also may include fatigue, weight loss and fever.

Some 900,000 people in the United States have UC, for which there is no cure, the FDA said in a news release.

Xeljanz was first approved in 2012 for rheumatoid arthritis, and in 2017 for psoriatic arthritis.

In clinical studies evaluating the pill's use for UC, the most common side effects were diarrhea, high cholesterol, headache, herpes zoster (shingles) infection, cold-like symptoms, rash and upper respiratory infection.

The drug's label includes the agency's most serious "boxed warning" of less common adverse reactions including serious infections and cancer, the FDA said.

The agency warned against using Xeljanz in tandem with biological therapies for UC, or with potent medications that suppress the body's immune system.

Xeljanz is produced by New York City-based Pfizer.

More information

Learn more from the FDA.


Copyright © 2013-2018 HealthDay. All rights reserved.

The Internet's Most Trusted Source For Mental Health Information
Sign up

Related Content

Addiction To Cocaine Sees Promising Cure In Near Future In Preventing Overdose
Addiction To Cocaine Sees Promising Cure In Near Future In Preventing Overdose

A radical gene therapy for drug addiction has been shown to dampen down cravings...

Read more
How Therapy Dogs Are Providing Significant Benefits To Children With ADHD
How Therapy Dogs Are Providing Significant Benefits To Children With ADHD

For children struggling with attention-deficit hyperactivity disorder (ADHD), vi...

Read more
The 4 Mistakes People With Anxiety Make & How To Prevent Them From Happening
The 4 Mistakes People With Anxiety Make & How To Prevent Them From Happening

I recently wrote a well-received post about five mistakes that people with depre...

Read more
Did You Know That 20% Autism Patients Were ALSO Diagnosed With Depression?
Did You Know That 20% Autism Patients Were ALSO Diagnosed With Depression?

Almost 20% of young people with autism spectrum disorder (ASD) also were diagnos...

Read more
Is There Anyone Else Out There With Bipolar Disorder & OCD Symptoms?
Is There Anyone Else Out There With Bipolar Disorder & OCD Symptoms?

It's not at all uncommon that I hear obsessive-compulsive (OC) symptoms as part ...

Read more
Signs Your Parent May Actually Have A Personality Disorder & How To...
Signs Your Parent May Actually Have A Personality Disorder & How To...

Have you always struggled in your relationship with your parent? Maybe your rela...

Read more