Study may explain why some triple-negative breast cancers are resistant to chemotherapy

Study may explain why some triple-negative breast cancers are resistant to chemotherapy

Triple-negative breast cancer (TNBC) is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment. A team at The University of Texas MD Anderson led a study which may explain how resistance evolves over time, and potentially which patients could benefit from chemotherapy. Results from a study led by Nicholas Navin, Ph.D., associate professor of Genetics, were published today in the April 19, 2018 online issue of Cell. Their findings indicate breast cancer cell resistance...

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