Why ‘Biomarkers’ Will Be Used to Detect Some Alzheimer’s Cases

Why ‘Biomarkers’ Will Be Used to Detect Some Alzheimer’s Cases

A new definition of Alzheimer’s disease could radically change how Alzheimer’s is diagnosed and treated. Guidelines published in the April issue of Alzheimer’s & Dementia reframe the Alzheimer’s diagnosis according to biological markers, or “biomarkers.” But this redefinition will be confined right now for the purpose of research, not for patients. According to the new guidelines, an Alzheimer’s disease diagnosis will now be based on three main biomarkers: the buildup of beta-amyloid proteins (plaques), tau proteins (tangles), and neurodegeneration. “The new definition is an attempt to better explain why you might have cognitive problems, number one,” said Dr. Jason Karlawish,...

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