Study Shows Fast-Acting Benefits of Ketamine for Depression and Suicidality; Caution on the Potential for Abuse and the Need for Effective Controls

Washington, D.C. – A nasal spray formulation of ketamine shows promise in the rapid treatment of symptoms of major depression and suicidal thoughts, according to a new study published online today in The American Journal of Psychiatry (AJP). The double-blind study compared the standard treatment plus esketamine, a nasal spray version of ketamine, to standard treatment plus a placebo for rapid treatment of symptoms of major depression, including suicidality, among individuals at imminent suicide risk. The study involved 68 participants randomly assigned to one of two groups – either receiving esketamine or placebo twice a week for four weeks. All...

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