Metabolic profiling may determine aggressiveness, prognosis of prostate cancer

A new approach to analyzing prostate gland tissue may help address a major challenge in treating prostate cancer -- determining which tumors are unlikely to progress and which could be life threatening and require treatment. In their report published in the journal Scientific Reports, Massachusetts General Hospital (MGH) investigators describe how cellular metabolites -- proteins produced as the results metabolic processes -- in apparently benign tissues from cancerous prostates not only can determine the grade and stage of the tumor but also can predict its risk of recurrence. "Prostate cancer detection through elevated PSA levels followed by prostate tissue biopsies...

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