New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing

To our knowledge this is the first study which combines relatively new, yet established computational techniques to identify additional treatments for a difficult to manage cerebral neoplasm. Beyond proposing already approved drug candidates in the management of atypical meningioma the study highlights the promise held by computational techniques in improving our management strategies. Gene expression profiling and use of drug expression profiles have yielded several plausible drug candidates for treating atypical meningioma, some of which have already been suggested by preceding studies. Although our analyses suggested multiple anti-tumour mechanisms for these drugs, further in vivo studies are required for validation...

Mental Health Does Not Come With A Manual, It Comes With Friends & Family Support That Never Gives Up!
Join now
Read more

Related Content

Addiction To Cocaine Sees Promising Cure In Near Future In Preventing Overdose
Addiction To Cocaine Sees Promising Cure In Near Future In Preventing Overdose

A radical gene therapy for drug addiction has been shown to dampen down cravings...

Read more
How Therapy Dogs Are Providing Significant Benefits To Children With ADHD
How Therapy Dogs Are Providing Significant Benefits To Children With ADHD

For children struggling with attention-deficit hyperactivity disorder (ADHD), vi...

Read more
The 4 Mistakes People With Anxiety Make & How To Prevent Them From Happening
The 4 Mistakes People With Anxiety Make & How To Prevent Them From Happening

I recently wrote a well-received post about five mistakes that people with depre...

Read more
Did You Know That 20% Autism Patients Were ALSO Diagnosed With Depression?
Did You Know That 20% Autism Patients Were ALSO Diagnosed With Depression?

Almost 20% of young people with autism spectrum disorder (ASD) also were diagnos...

Read more
Is There Anyone Else Out There With Bipolar Disorder & OCD Symptoms?
Is There Anyone Else Out There With Bipolar Disorder & OCD Symptoms?

It's not at all uncommon that I hear obsessive-compulsive (OC) symptoms as part ...

Read more
Signs Your Parent May Actually Have A Personality Disorder & How To...
Signs Your Parent May Actually Have A Personality Disorder & How To...

Have you always struggled in your relationship with your parent? Maybe your rela...

Read more