Altered cerebral hemodyamics and cortical thinning in asymptomatic carotid artery stenosis

Cortical thinning is a potentially important biomarker, but the pathophysiology in cerebrovascular disease is unknown. We investigated the association between regional cortical blood flow and regional cortical thickness in patients with asymptomatic unilateral high-grade internal carotid artery disease without stroke. Twenty-nine patients underwent high resolution anatomical and single-delay, pseudocontinuous arterial spin labeling magnetic resonance imaging with partial volume correction to assess gray matter baseline flow. Cortical thickness was estimated using Freesurfer software, followed by co-registration onto each patient’s cerebral blood flow image space. Paired t-tests assessed regional cerebral blood flow in motor cortex (supplied by the carotid artery) and visual...

Mental Health Does Not Come With A Manual, It Comes With Friends & Family Support That Never Gives Up!
Join now
Read more

Related Content

What If Your Anxiety & Depression Is Really A Sign Of ADHD?
What If Your Anxiety & Depression Is Really A Sign Of ADHD?

More often than not, when a person over the age of 10 is diagnosed with attentio...

Read more
New Patent By OxyContin Maker May Treat Pain But Comes With Addictive Potential
New Patent By OxyContin Maker May Treat Pain But Comes With Addictive Potential

Purdue Pharma, the maker of OxyContin, has received a patent designed to treat o...

Read more
Why Are Transgenders Experiencing More Mental Health Issues Than The General Public?
Why Are Transgenders Experiencing More Mental Health Issues Than The General Public?

Individuals who identify as transgender tend to experience higher rates of menta...

Read more
New Research In Schizophrenia Shows That A Video Game Can Aid In Preventing Hallucinations
New Research In Schizophrenia Shows That A Video Game Can Aid In Preventing Hallucinations

People with schizophrenia can be trained by playing a video game to control the ...

Read more
I was 12 When I Survived 9-11 But My Peers & I Are Only Now Realizing Our PTSD
I was 12 When I Survived 9-11 But My Peers & I Are Only Now Realizing Our PTSD

As the Twin Towers burned and eventually collapsed on 9/11, I was running from m...

Read more
How Running Helped These Everyday People Beat OCD, Depression & Anxiety
How Running Helped These Everyday People Beat OCD, Depression & Anxiety

When documentary photographer Martin Eberlen was diagnosed with ADHD in his earl...

Read more