Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

A once-weekly, injectable, extended-release formulation of exenatide, an exendin-4–based GLP-1 receptor agonist approved for the treatment of type 2 diabetes, has been shown to lower blood glucose and induce modest decreases in body weight, blood pressure, and lipid levels 15,16 but has also been shown to increase heart rate. 17,18 In accordance with regulatory guidance, 19,20 the Exenatide Study of Cardiovascular Event Lowering (EXSCEL) assessed the long-term cardiovascular safety and efficacy of exenatide, administered once weekly, in patients with type 2 diabetes who had a wide range of cardiovascular risk. The risk of death from any cause among persons with...

The Internet's Most Trusted Source For Mental Health Information
Sign up
Read more

Related Content

What If Your Anxiety & Depression Is Really A Sign Of ADHD?
What If Your Anxiety & Depression Is Really A Sign Of ADHD?

More often than not, when a person over the age of 10 is diagnosed with attentio...

Read more
New Patent By OxyContin Maker May Treat Pain But Comes With Addictive Potential
New Patent By OxyContin Maker May Treat Pain But Comes With Addictive Potential

Purdue Pharma, the maker of OxyContin, has received a patent designed to treat o...

Read more
Why Are Transgenders Experiencing More Mental Health Issues Than The General Public?
Why Are Transgenders Experiencing More Mental Health Issues Than The General Public?

Individuals who identify as transgender tend to experience higher rates of menta...

Read more
New Research In Schizophrenia Shows That A Video Game Can Aid In Preventing Hallucinations
New Research In Schizophrenia Shows That A Video Game Can Aid In Preventing Hallucinations

People with schizophrenia can be trained by playing a video game to control the ...

Read more
I was 12 When I Survived 9-11 But My Peers & I Are Only Now Realizing Our PTSD
I was 12 When I Survived 9-11 But My Peers & I Are Only Now Realizing Our PTSD

As the Twin Towers burned and eventually collapsed on 9/11, I was running from m...

Read more
How Running Helped These Everyday People Beat OCD, Depression & Anxiety
How Running Helped These Everyday People Beat OCD, Depression & Anxiety

When documentary photographer Martin Eberlen was diagnosed with ADHD in his earl...

Read more