A combination of two drugs may be twice as effective in shrinking metastatic melanomas than a single medication, a new clinical trial finds. The drugs, Yervoy and Imlygic, more than doubled the percentage of patients whose tumors shrank, compared to those treated with Yervoy alone.
Imyligc kills cancer cells by infecting them, while Yervoy is an immunotherapy medication. The treatment also completely removed tumors in 13% of the patients, and shrank some tumors that weren’t directly injected with the drugs.
However, the combination of Yervoy and Imlygic made certain side effects stronger, like nausea, diarrhea, chills, fatigue, itching, and rash.